Více jak 30 studií potvrzují protirakovinné účinky látky Indol-3-Karbinol. Tady je pár z pár z nich:

 

  • Brew et.al. Int J Cancer PMC 2012 July 19 – Indole-3-carbinol inhibits MDA-MB-231 breast cancer cell motility and induces stress fibers and focal adhesion formation by activation of Rho kinase activity – Studie se nachází ZDE
  • Galluzi et.al. PLoS One. 2012; 7(8): e43249 – Induction of Endoplasmic Reticulum Stress Response by the Indole-3-Carbinol Cyclic Tetrameric Derivative CTet in Human Breast Cancer Cell Lines – Studie se nachází ZDE
  • Marconett et.al. Carcinogenesis. 2011 September; 32(9): 1315–1323 – Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promoter and mediates the G1 cell cycle arrest of human breast cancer cells – Studie se nachází ZDE
  • Weng et.al. Cancer Lett. 2008 April 18; 262(2): 153 – Indole-3-carbinol as a chemopreventive and anti-cancer agent – Studie se nachází ZDE
  • Garikapaty et al. Oncol Rep. 2005 Jan;13(1):89-93 – Anti-carcinogenic and anti-metastatic properties of indole-3-carbinol in prostate cancer
  • Bell, et al. Gynecol Oncol. 2000 Aug;78(2):123-9 – Placebo-controlled trial of indole-3-carbinol in the treatment of CIN
  • Wong et al. J Cell Biochem Suppl. 1997;28-29:111-6 – Dose-ranging study of indole-3-carbinol for breast cancer prevention
  • Grubbs et al. Anticancer Res. 1995 May-Jun;15(3):709-16 – Chemoprevention of chemically-induced mammary carcinogenesis by indole-3-carbinol